Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ InSolution™ U0126
A potent and specific inhibitor of MEK1 and MEK2 .
MilliporeSigma™ Calbiochem™ InSolution™ Y-27632
Y-27632A, CAS 146986-50-7, is a cell-permeable, reversible, inhibitor of Rho kinases (Ki = 140 nM for p160ROCK). Enhances survival & cloning efficiency of ESC without affecting their pluripotency.
MilliporeSigma™ Calbiochem™ Vincristine Sulfate, Apocynaceae sp.
Indole alkaloid that binds to tubulin, inhibiting formation of microtubules.
MilliporeSigma™ Calbiochem™ Valproic Acid, Sodium Salt
A cell-permeable, short-chained fatty acid that inhibits histone deacetylase (IC50 = 400 μM for HDAC1).
MilliporeSigma™ Calbiochem™ VEGFR3 Kinase Inhibitor, MAZ51
The VEGFR3 Kinase Inhibitor, MAZ51, also referenced under CAS 163655-37-6, controls the biological activity of VEGFR3 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Wnt Antagonist III, Box5
The Wnt Antagonist III, Box5 controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Wnt Antagonist II, IWP-2
The Wnt Antagonist II, IWP-2, also referenced under CAS 686770-61-6, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ VEGF Inhibitor, V1
The VEGF Inhibitor, V1 controls the biological activity of VEGF. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Wnt Agonist I in DMSO
The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ (±)-Verapamil, Hydrochloride
A papaverine derivative that blocks Ca2+ channels (principally the L-type) in smooth and cardiac muscle cells.
MilliporeSigma™ Calbiochem™ Glycogen Phosphorylase Inhibitor
The Glycogen Phosphorylase Inhibitor, also referenced under CAS 648926-15-2, controls the biological activity of Glycogen Phosphorylase.
MilliporeSigma™ Calbiochem™ GSK-3β Inhibitor VIII
The GSK-3β Inhibitor VIII, also referenced under CAS 487021-52-3, controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Akt Activator II, SC79
Akt Activator II, SC79, CAS 305834-79-1, is a cell-permeable compound that interacts with Akt PH domain PIP3 binding pocket and makes it more susceptible to phosphorylation by upstream Kinases.
MilliporeSigma™ Calbiochem™ Cypermethrin
Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 40 pM). May also have varied effects on ion channels.
MilliporeSigma™ Calbiochem™ Cyclophosphamide Monohydrate
A widely used anti-neoplastic agent that also displays immunosuppressant properties.